Perfusion Changes in Perforator-Based Propeller Flaps

Background To cover soft tissue defects, the perforator-based propeller flap offers the option to rotate healthy tissue into complex wounds.By rotating the flap, the perforator is torqued.As a result, perfusion changes are possible.Methods A retrospective data analysis of patients was done, who received a propeller flap to cover soft tissue defects

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Pedicle screw insertion into infected vertebrae reduces operative time and range of fixation in minimally invasive posterior fixation for thoracolumbar pyogenic spondylitis: a multicenter retrospective cohort study

Abstract Background Minimally invasive posterior fixation surgery for pyogenic spondylitis is known to reduce invasiveness and complication rates; however, the outcomes of concomitant insertion of pedicle screws (PS) into the infected vertebrae via the posterior approach are undetermined.This study aimed to assess the safety and efficacy of PS inse

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Syntaxin 18 regulates the DNA damage response and epithelial-to-mesenchymal transition to promote radiation resistance of lung cancer

Abstract Radiotherapy is an important modality in lung cancer treatment.Despite advances in treatment planning and dose delivery, patient benefit is still limited by in-field relapse and metastatic recurrence.Simultaneous application of cisplatinum-based chemotherapy leads to moderately improved outcomes, thus providing proof-of-concept for radiose

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